Associate Professor of Biomedical Engineering
Pritzker Institute of Biomedical Science and Engineering

Illinois Institute of Technology
Engineering 1 Building, Room 116
10 W. 32 nd Street
Chicago, IL 60616

Phone: 312.567.3926
Fax: 312.567.5707
Email: anastasio@iit.edu

Education
BS Electrical Engineering, 1992, Illinois Institute of Technology
MSE Electrical Engineering, 1993, University of Pennsylvania
MS Physics, 1995, University of Illinois at Chicago
PhD Medical Physics, 2001, The University of Chicago

Honors
- 2003 Whitaker Foundation Fellow
- 2006 NSF CAREER Award - Development of Biomedical X-ray Phase-Contrast Tomography
- 2006 IIT Sigma Xi Award for Excellence in Research

Research interests
Dr. Anastasio’s research interests include mathematical and numerical aspects of inverse problems in bioimaging, tomographic image reconstruction, wave physics-based imaging modalities, and theoretical image science.

Current research projects
- Development of X-ray phase-contrast tomography (NIH/NIBIB)
- Development of local tomography for image-guided therapy (NIH/NCI,Whitaker Foundation)
- Reconstruction theory for intensity diffraction tomography (optical tomography) (NIH/NIBIB)
- Acoustic imaging and inverse scattering
- Development of thermoacoustic/photoacoustic tomography

Other technical activities
- Guest Associate Editor, Medical Physics, 2005-present
- Member, IEEE, OSA, and SPIE
- Reviewer for NSF, DoD, and 15 Journals

Selected journal papers

1. M. A. Anastasio, H. Yoshida, R. Nagel, R. Nishikawa, and K. Doi: A Genetic Algorithm-Based Method for Optimizing Performance of a Computer-Aided Diagnosis Scheme for Detection of Clustered Microcalcifications in mammograms, Medical Physics, 25, 1613-1620, 1998.
2. M. A. Anastasio, M. Kupinski, and X. Pan: Noise Properties in Diffraction Tomography: Comparison of Conventional Reconstruction Algorithms with a New Algorithm, IEEE Transactions on Nuclear Science, 45, 2216-2223, 1998.
3. M. A. Anastasio, M. Kupinski, and R. Nishikawa: Optimization and FROC Analysis of Rule-Based Detection Schemes Using a Multiobjective Approach , IEEE Transactions on Medical Imaging, 17, 1089-1093, 1998.
4. M. A. Anastasio, X. Pan, and C. Kao: Multi-Dimensional Smoothing Using Orthogonal Expansions, IEEE Signal Processing Letters, 6, 91-94, 1998.
5. X. Pan, M. A. Anastasio, and C. Kao: A Comparative Study of Image Reconstruction in SPECT and Diffraction Tomography, IEEE Transactions on Nuclear Science, 46, 527-534, 1999.
6. M. Kupinski and M. A. Anastasio: Multiobjective Genetic Optimization of Diagnostic classifiers with Implications for Generating ROC Curves, IEEE Transactions on Medical Imaging, 18, 675-685, 1999.
7. C. Kao, X. Pan, P. La Riviere, and M. A. Anastasio: A Fourier-Based Optimal Recovery Approach for Anti-Aliasing Interpolation, Optical Engineering, 38, 2041-2044, 1999.
8. X. Pan and M. A. Anastasio: Short-Scan Filtered Backpropagation Algorithms for Diffraction Tomography, Journal of the Optical Society of America A, 16, 2896-2903, 1999.
9. M. A. Anastasio and X. Pan: Computationally Efficient and Statistically Robust Image Reconstruction in 3D Diffraction Tomography, Journal of the Optical Society of America A, 17, 391-400, 2000.
10. M. A. Anastasio and X. Pan: A New Reconstruction Algorithm for Reflection Mode Diffraction Tomography, IEEE Transactions on Image Processing, 9, 1262-1271, 2000.
11. M. A. Anastasio and X. Pan: Investigation of the Noise Properties of an Infinite Class of Reconstruction Methods in Diffraction Tomography, International Journal of Imaging Systems and Technology, 10, 437-446, 2000.
12. M. A. Anastasio and X. Pan: Full- and Minimal-Scan Reconstruction Algorithms for Fan-Beam Diffraction Tomography, Applied Optics, 40, 3334-3345, 2001 .
13. M. A. Anastasio, X. Pan and E. Clarkson: Comments on the Filtered Backprojection Algorithm, Range Conditions, and the Pseudoinverse Solution, IEEE Transactions on Medical Imaging, 20:6, 539-542, 2001.
14. M. A. Anastasio and X. Pan: Numerically Robust Minimal-Scan Reconstruction Algorithms for Diffraction Tomography via Radon Transform Inversion, International Journal of Imaging Systems and Technology, 12,84-91, 2002.
15. X. Pan and M. A. Anastasio: On a Limited-View Reconstruction Problem in Diffraction Tomography, IEEE Transactions on Medical Imaging, 21, 413-416, 2002.
16. X. Pan, Y. Zou and M. A. Anastasio: Data Redundancy and Reduced-Scan Reconstruction in Reflectivity Tomography, IEEE Transactions on Image Processing, 12, 784-795, 2003.
17. M. A. Anastasio and X. Pan: An improved reconstruction algorithm for 3D diffraction tomography with spherical-wave sources, IEEE Transactions on Biomedical Engineering, 50, 517-521, 2003.
18. M. A. Anastasio, D. Shi, X. Pan, C. Pelizzari, and P. Munro: A Preliminary Investigation of Local Tomography for Megavoltage CT Imaging, Medical Physics, 30, 2969-2980, 2003.
19. M. Wernick, O. Wirjadi, D. Chapman, Z. Zhong, N. Galatsanos, Y. Yang, J. Brankov, O. Oltulu, M. A. Anastasio, and C. Muehleman: Multiple-Image Radiography, Physics in Medicine and Biology, 48, 3875-3895, 2003.
20. M. A. Anastasio, D. Shi, F. De Carlo, and X. Pan: Analytic Image Reconstruction in Local Phase-Contrast Tomography, Physics in Medicine and Biology, 49, 121-144, 2004.
21. D. Shi, M. A. Anastasio, Y. Huang, and G. Gbur: Half-Scan and Single-Plane Intensity Diffraction Tomography for Phase Objects, Physics in Medicine and Biology, 49, 2733-2752, 2004.
22. G. Gbur, M. A. Anastasio, D. Shi, Y. Huang: Spherical Wave Intensity Diffraction Tomography, Journal of the Optical Society of America A, 22 ,230-238, 2005.
23. M. A. Anastasio, J. Zhang, X. Pan, Y. Zou, G. Ku, and L. Wang: Half-Time Image Reconstruction in Thermoacoustic Tomography, IEEE Transactions on Medical Imaging, 24, 199-210, 2005.
24. K. Arfanakis, A. A. Tamhane, J.G. Pipe, and M. A. Anastasio: K-space Undersampling in PROPELLER Imaging, Magn. Reson. Med., 53, 675-683, 2005.
25. D. Shi, M. A. Anastasio, and X. Pan: Reconstruction of Refractive Index Discontinuities from Truncated Phase-Contrast Tomography Projections, Applied Physics Letters, 86, 034102, 2005.
26. J. Zhang, M. A. Anastasio, X. Pan, and L.V. Wang: Weighted EM Reconstruction Algorithms for Thermoacoustic Tomography, IEEE Transactions on Medical Imaging, 24, 817-820, 2005.
27. M. A. Anastasio, D. Shi, Y. Huang, and G. Gbur: Image Reconstruction in Spherical Wave Intensity Diffraction Tomography, Journal of the Optical Society of America A, 22, 2651-2661, 2005.
28. M. A. Anastasio, J. Zhang, E.Y. Sidky, Y. Zou, D. Xia, and X. Pan: Feasibility of Half-Data Image Reconstruction in 3D Reflectivity Tomography with a Spherical Aperture, IEEE Transactions on Medical Imaging, 24, 1100-1112, 2005.
29. M. A. Anastasio, E. Y. Sidky, Y. Zou, and X. Pan: Boundary Reconstruction on Chords in Cone-Beam Tomography (Invited Paper), , J. Stereo.Image Analys., 10:137-140, Chinese 2005.
30. J. Zhang, D. Shi, M. A. Anastasio, J. Sillanpaa, and J. Chang: Weighted Expectation Maximization Reconstruction Algorithms with Application to Gated Megavoltage Tomography, Physics in Medicine and Biology, 50, N299-N307, 2005.
31. J. Brankov, M. Wernick, D. Chapman, Y. Yang, C. Muehleman. Z. Zhong, and M. A. Anastasio: A computed tomography implementation of Multiple-Image Radiography, Medical Physics, 33:2, 278-289, 2006.
32. M. A. Anastasio, D. Shi, and G. Gbur: Multi-Spectral Intensity Diffraction Tomography: Quasi-Nondispersive Objects, Journal of the Optical Society of America A, 23, 1359-1368, 2006.
33. G. Khelashvili, J.G. Brankov, D. Chapman, M. A. Anastasio, Y. Yang, Z. Zhong, and M. N. Wernick: A Physical Model of Multiple Image Radiography, Physics in Medicine and Biology, 51, 221-236, 2006.
34. D. Shi and M. A. Anastasio: Off-axis Holographic Tomography for Diffracting Scalar Wavefields, Physical Review E, 73, 016612, 2006.
35. P. J. La Riviere, J. Zhang, and M. A. Anastasio: Image Reconstruction in Optoacoustic Tomography for Dispersive Acoustic Media, Optics Letters, 31, 781-783, 2006.
36. Yin Huang and M. A. Anastasio: Statistically Principled use of In-line Measurements in Intensity Diffraction Tomography, Journal of the Optical Society of America A, 24, 626-642, 2007.
37. M. A. Anastasio, Y. Zou, E.Y. Sidky, and X. Pan: Local Cone-Beam Tomography Image Reconstruction on Chords, Journal of the Optical Society of America A, 24, 1569-1579, 2007.
38. C-Y Chou, M. A. Anastasio, J.B. Brankov, M.W. Wernick, E. Brey, D. Connor and Z. Zhong: An Extended DEI Method for Implementing Multiple-Image Radiography, 52, 1923-1945, 2007.
39. D. Shi and M. A. Anastasio: Intensity Diffraction Tomography with a Fixed Detector Plane, Optical Engineering, (In press), 2007.
40. C-Y Chou, Y. Huang, D. Shi and M. A. Anastasio: Image Reconstruction in Quantitative X-ray Phase-Contrast Imaging Employing Multiple Measurements, Optics Express, (In press), 2007.
41. M. A. Anastasio and X. Pan: Region-of-Interest Imaging in Differential Phase-Contrast Tomography, Optics Letters, (In press), 2007.